3-HO-PCP Arylcyclohexylamines

gram(s)

Status: AVAILABLE [10/05/2026]


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1 to 2 EUR 47.95 /gram Save 0%
3 to 4 EUR 43.16 /gram Save 10%
5 to 9 EUR 38.36 /gram Save 20%
10 to 24 EUR 31.17 /gram Save 35%
25 + EUR 26.37 /gram Save 45%

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3-Hydroxyphencyclidine (commonly known as 3-HO-PCP) is a novel dissociative substance of the arylcyclohexylamine class that produces potent dissociative, hallucinogenic and euphoric effects when administered. In addition to its primary activity as a NMDA receptor antagonist, it has been found to have appreciable affinity for the μ-opioid receptor. 3-HO-PCP was first synthesized in 1978 to investigate the structure-activity relationship of Phencyclidine (PCP) derivatives. It was further explored alongside PCP in the 1980s, where it was discovered to possess μ-opioid agonist activity in animal models. Like other substances of its class, particularly Methoxetamine (MXE), Phencyclidine (PCP), and 3-MeO-PCE, it is known to primarily induce a state referred to as "dissociative anesthesia", albeit the extent to which this occurs has been reported to be highly dose-dependent and variable in its effects.

AN USER EXPERIENCE ABOUT 3-HO-PCP:
... This was a great experience for me and it really changed my perspective on PCP and its analogues. I can see how this experience could ramp up into something scary if somebody took too much, but with proper dosing, set and setting, and experience, this substance offers a unique and enjoyable dissociative experience. I was using it in a social setting so I was mainly just chatting and hanging out with friends, but I could see how solo trips would be very introspective. Definitely will try this substance again, it may be my new favorite dissociative but only time will tell. Anyone out there who decides to try it themselves, PLEASE be careful. Do not exceed 8-10mg in a 6 hour period or you may experience manic/psychotic effects. Be safe, be smart, and treat your brain with respect! ...
How to Buy 3-HO-PCP

Discover and purchase 3-HO-PCP along with a variety of other research chemicals at Shulgin's Lab. We ensure that all our chemicals undergo rigorous third-party lab testing for quality and safety. If you're interested in viewing the HNMR results for 3-HO-PCP or any other chemical, feel free to reach out to us via email at

Engaging in Responsible Research with 3-HO-PCP

It is essential to engage in responsible research practices. We encourage you to thoroughly read and educate yourself before conducting any research with chemicals. The Psychonaut Wiki offers valuable resources and insights on 3-HO-PCP, as does The Third Wave. Always ensure you have a solid understanding of a chemical before proceeding with any research.


Please note that 3-HO-PCP and all other products are intended strictly for research purposes and are not suitable for human consumption.

Store 3-HO-PCP in a cool, dry place away from sunlight.


3-HO-PCP stock last updated at: May 2026